My baby 11 months have yellow in her palm and foot. It made me worry, I thought she got yellow illness, but after that I saw her eye, the eyes not yellow, also the color of her feces not changes, she also don't have fever. So, I was thinking this is something different. Then I try to check in internet about this and I found this information, hopeful can help mom in the world.
What is Hypercarotenemia?
Carotenaemia (xanthaemia) is the presence in blood of the yellow pigment carotene from excessive intake of carrots or other vegetables containing the pigment resulting in increased serum carotenoids. It can lead to subsequent yellow-orange discoloration (xanthoderma or carotenoderma) and their subsequent deposition in the outermost layer of skin. The number of cases reported per year has tripled in recent years. Carotenoids are lipid-soluble compounds that include alpha- and beta-carotene, beta-cryptoxanthin, lycopene, lutein, and zeaxanthin. The primary serum carotenoids are beta-carotene, lycopene, and lutein. Serum levels of carotenoids vary between region, ethnicity, and sex in the healthy population. All are absorbed by passive diffusion from the gastrointestinal tract and are then partially metabolized in the intestinal mucosa and liver to vitamin A. From there they are transported in the plasma into the peripheral tissues. Carotenoids are eliminated via sweat, sebum, urine, and gastrointestinal secretions. Carotenoids contribute to normal-appearing human skin color and are a significant component of physiologic ultraviolet photoprotection.
Carotenemia is a benign condition most commonly occurring in vegetarians and young children. Carotenemia is more easily appreciated in light-complexioned people, and it may present chiefly as an orange discolouration of the palms and the soles in more darkly pigmented persons. Carotenemia does not cause selective orange discoloration of the sclerae of the eyes, and thus is usually easy to distinguish from the yellowing of the skin caused by bile pigments in states of jaundice.
Carotenoderma is deliberately caused by beta-carotenoid treatment of certain photo-sensitive dermatitis diseases such as erythropoietic protoporphyria, where beta carotene in quantities which discolor the skin is prescribed. These high doses of beta carotene have been found to be harmless in studies, though cosmetically displeasing to some. In a recent meta analysis of these treatments, however, the effectiveness of the treatment has been called into question.
How it Causes ?
There are three main mechanisms involved in hypercarotenemia: excessive dietary intake of carotenoids, increased serum lipids, and decreased metabolism of carotenoids. The most common reported cause of hypercarotenemia (and thus carotenoderma) is increased intake, either through increased dietary foods or nutritional supplements. This change takes approximately 4 to 7 weeks to be recognized clinically. Numerous ingested substances are rich in carotenoids. Increased serum lipids also cause hypercarotenemia because there are increased circulating lipoproteins that contain bound carotenoids. Finally, in certain disease states, the metabolism and conversion of carotenoids to retinol is slowed, which can lead to decreased clearance and increased plasma levels.
Carotenoderma can be divided into two major types, primary and secondary. Primary carotenoderma is that developing from increased oral ingestion of carotenoids, whereas secondary carotenoderma is caused from underlying disease states that increase serum carotenoids with normal oral intake of these compounds. Primary and secondary carotenoderma can coexist in the same patient.
Foods associated with high levels of carotenoids include:
- Alfalfa
- Apples
- Apricots
- Asparagus
- Beans
- Beet greens
- Broccoli
- Brussels sprouts
- Butter
- Cabbage
- Cantaloupes
- Carrots
- Cheese
- Collard greens
- Cucumbers
- Eggs
- Figs
- Kale
- Kiwi
- Lettuce
- Mangoes
- Milk
- Mustard
- Oranges
- Palm oil
- Papayas
- Parsley
- Peaches
- Pineapples
- Plums
- Pumpkins
- Seaweed
- Spinach
- Squash
- Sweet potatoes
- Tomatoes
- Yams
- Yellow corn
How is the treatment?
Carotenemia and carotenoderma is in itself harmless, and does not require treatment. In primary carotenoderma, when the use of high quantities of carotene is discontinued the skin color will return to normal. It may take up to several months, however, for this to happen. Infants with this condition should not be taken off prescribed vitamin supplements unless advised to do so by the child's pediatrician.
source: wikipedia
Label:
Carotenaemia,
Hypercarotenemia,
yellow feet,
yellow hand
0 komentar:
Posting Komentar